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ea0035p387 | Diabetes (epidemiology, pathophysiology) | ECE2014

The HLA-A*33 haplotype enhances the risk of type 1 diabetesin ndividuals with HLA-DR3+ or DR9+ haplotype

Zhang Juanjuan , Gu Weiqiong , Wang Bokai , Gao Jie , Li Li , Cui Bin , Hong Jie , Wang Weiqing , Ning Guang

Background: To investigate the typing for HLA-I in Chinese patients with type 1 diabetes (T1D) as a complement screening for HLA-II.Methods: A total of 212 T1D patients and 200 healthy controls were enrolled. The genetic polymorphisms of HLA-I and II were examined with a high-resolution polymerase chain reaction-sequence-based typing method.Results: The novel haplotype, A*33:03-B*58:01-C*03:02(A33), was a...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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